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One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge()

Human infections with a novel influenza A H7N9 subtype virus were reported in China recently. The virus caused severe disease with high mortality rates and it raised concerns over its pandemic potential. Here, we assessed in the mouse model protective efficacy of single immunisations with low vaccin...

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Detalles Bibliográficos
Autores principales: Klausberger, Miriam, Wilde, Monika, Palmberger, Dieter, Hai, Rong, Albrecht, Randy A., Margine, Irina, Hirsh, Ariana, García-Sastre, Adolfo, Grabherr, Reingard, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906608/
https://www.ncbi.nlm.nih.gov/pubmed/24262313
http://dx.doi.org/10.1016/j.vaccine.2013.11.036