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Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old()

Inherited genetic variation of mitochondrial DNA (mtDNA) could account for the missing heritability of human longevity and healthy aging. Here, we show no robust association between common genetic variants of mtDNA and frailty (an “unhealthy aging” phenotype) or mortality in 700, more than 85-year-o...

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Detalles Bibliográficos
Autores principales:	Collerton, Joanna, Ashok, Deepthi, Martin-Ruiz, Carmen, Pyle, Angela, Hudson, Gavin, Yadegarfar, Mohammad, Davies, Karen, Jagger, Carol, von Zglinicki, Thomas, Kirkwood, Thomas B.L., Chinnery, Patrick F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2013
Materias:	Genetic Reports Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906612/ https://www.ncbi.nlm.nih.gov/pubmed/23639206 http://dx.doi.org/10.1016/j.neurobiolaging.2013.04.001

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