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PNU-91325 increases fatty acid synthesis from glucose and mitochondrial long chain fatty acid degradation: a comparative tracer-based metabolomics study with rosiglitazone and pioglitazone in HepG2 cells

The mitochondrial membrane protein termed “mitoNEET,” is a putative secondary target for insulin-sensitizing thiazolidinedione (TZD) compounds but its role in regulating metabolic flux is not known. PNU-91325 is a thiazolidinedione derivative which exhibits high binding affinity to mitoNEET and lowe...

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Detalles Bibliográficos
Autores principales:	Harrigan, George G., Colca, Jerry, Szalma, Sándor, Boros, László G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Kluwer Academic Publishers-Plenum Publishers 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906712/ https://www.ncbi.nlm.nih.gov/pubmed/24489530 http://dx.doi.org/10.1007/s11306-006-0015-5

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