Enlightened Mannhemia haemolytica lung inflammation in bovinized mice

Polymorphonuclear cells diapedesis has an important contribution to the induced Mannhemia haemolytica (M. haemolytica) infection lung inflammation and IL-8 is the primary polymorphonuclear chemoattractant. Using a bovine IL-8/luciferase transiently transgenized mouse model, the orchestration among M...

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Detalles Bibliográficos
Autores principales: Stellari, Fabio Franco, Lavrentiadou, Sophia, Ruscitti, Francesca, Jacca, Sarah, Franceschi, Valentina, Civelli, Maurizio, Carnini, Chiara, Villetti, Gino, Donofrio, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906860/
https://www.ncbi.nlm.nih.gov/pubmed/24460618
http://dx.doi.org/10.1186/1297-9716-45-8
Descripción
Sumario:Polymorphonuclear cells diapedesis has an important contribution to the induced Mannhemia haemolytica (M. haemolytica) infection lung inflammation and IL-8 is the primary polymorphonuclear chemoattractant. Using a bovine IL-8/luciferase transiently transgenized mouse model, the orchestration among M. haemolytica, IL-8 promoter activation and neutrophilia was followed in real time by in vivo image analysis.

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