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Noise propagation through extracellular signaling leads to fluctuations in gene expression

BACKGROUND: Cell-to-cell variability in mRNA and proteins has been observed in many biological systems, including the human innate immune response to viral infection. Most of these studies have focused on variability that arises from (a) intrinsic stochastic fluctuations in gene expression and (b) e...

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Detalles Bibliográficos
Autores principales: Tabbaa, Omar P, Nudelman, German, Sealfon, Stuart C, Hayot, Fernand, Jayaprakash, Ciriyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906959/
https://www.ncbi.nlm.nih.gov/pubmed/24067165
http://dx.doi.org/10.1186/1752-0509-7-94