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Identification and Validation of an Anthracycline/Cyclophosphamide–Based Chemotherapy Response Assay in Breast Cancer

BACKGROUND: There is no method routinely used to predict response to anthracycline and cyclophosphamide–based chemotherapy in the clinic; therefore patients often receive treatment for breast cancer with no benefit. Loss of the Fanconi anemia/BRCA (FA/BRCA) DNA damage response (DDR) pathway occurs i...

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Detalles Bibliográficos
Autores principales:	Mulligan, Jude M., Hill, Laura A., Deharo, Steve, Irwin, Gareth, Boyle, David, Keating, Katherine E., Raji, Olaide Y., McDyer, Fionnuala A., O’Brien, Eamonn, Bylesjo, Max, Quinn, Jennifer E., Lindor, Noralane M., Mullan, Paul B., James, Colin R., Walker, Steven M., Kerr, Peter, James, Jacqueline, Davison, Timothy S., Proutski, Vitali, Salto-Tellez, Manuel, Johnston, Patrick G., Couch, Fergus J., Paul Harkin, D., Kennedy, Richard D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906990/ https://www.ncbi.nlm.nih.gov/pubmed/24402422 http://dx.doi.org/10.1093/jnci/djt335

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