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HIF-1-Dependent Induction of Jumonji Domain-Containing Protein (JMJD) 3 under Hypoxic Conditions

Jumonji domain-containing proteins (JMJD) catalyze the oxidative demethylation of a methylated lysine residue of histones by using O(2), α-ketoglutarate, vitamin C, and Fe(II). Several JMJDs are induced by hypoxic stress to compensate their presumed reduction in catalytic activity under hypoxia. In...

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Detalles Bibliográficos
Autores principales:	Lee, Ho-Youl, Choi, Kang, Oh, Hookeun, Park, Young-Kwon, Park, Hyunsung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korea Society for Molecular and Cellular Biology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907005/ https://www.ncbi.nlm.nih.gov/pubmed/24552709 http://dx.doi.org/10.14348/molcells.2014.2250

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