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Using phage display selected antibodies to dissect microbiomes for complete de novo genome sequencing of low abundance microbes
BACKGROUND: Single cell genomics has revolutionized microbial sequencing, but complete coverage of genomes in complex microbiomes is imperfect due to enormous variation in organismal abundance and amplification bias. Empirical methods that complement rapidly improving bioinformatic tools will improv...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907030/ https://www.ncbi.nlm.nih.gov/pubmed/24279426 http://dx.doi.org/10.1186/1471-2180-13-270 |