The S40 residue in HIV-1 Gag p6 impacts local and distal budding determinants, revealing additional late domain activities

BACKGROUND: HIV-1 budding is directed primarily by two motifs in Gag p6 designated as late domain-1 and −2 that recruit ESCRT machinery by binding Tsg101 and Alix, respectively, and by poorly characterized determinants in the capsid (CA) domain. Here, we report that a conserved Gag p6 residue, S40,...

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Detalles Bibliográficos
Autores principales: Watanabe, Susan M, Chen, Min-Huei, Khan, Mahfuz, Ehrlich, Lorna, Kemal, Kimdar Sherefa, Weiser, Barbara, Shi, Binshan, Chen, Chaoping, Powell, Michael, Anastos, Kathryn, Burger, Harold, Carter, Carol A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907034/
https://www.ncbi.nlm.nih.gov/pubmed/24257210
http://dx.doi.org/10.1186/1742-4690-10-143

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