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In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis
BACKGROUND: The HIV-1 accessory protein, Nef, is decisive for progression to AIDS. In vitro characterization of the protein has described many Nef activities of unknown in vivo significance including CD4 downregulation and a number of activities that depend on Nef interacting with host SH3 domain pr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907037/ https://www.ncbi.nlm.nih.gov/pubmed/24172637 http://dx.doi.org/10.1186/1742-4690-10-125 |