Cargando…
Deep Sequencing of Viral Genomes Provides Insight into the Evolution and Pathogenesis of Varicella Zoster Virus and Its Vaccine in Humans
Immunization with the vOka vaccine prevents varicella (chickenpox) in children and susceptible adults. The vOka vaccine strain comprises a mixture of genotypes and, despite attenuation, causes rashes in small numbers of recipients. Like wild-type virus, the vaccine establishes latency in neuronal ti...
Autores principales: | Depledge, Daniel P., Kundu, Samit, Jensen, Nancy J., Gray, Eleanor R., Jones, Meleri, Steinberg, Sharon, Gershon, Anne, Kinchington, Paul R., Schmid, D. Scott, Balloux, Francois, Nichols, Richard A., Breuer, Judith |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907055/ https://www.ncbi.nlm.nih.gov/pubmed/24162921 http://dx.doi.org/10.1093/molbev/mst210 |
Ejemplares similares
-
Rates of Vaccine Evolution Show Strong Effects of Latency: Implications for Varicella Zoster Virus Epidemiology
por: Weinert, Lucy A., et al.
Publicado: (2015) -
Evolution of Cocirculating Varicella-Zoster Virus Genotypes during a Chickenpox Outbreak in Guinea-Bissau
por: Depledge, Daniel P., et al.
Publicado: (2014) -
Coevolution of Sites under Immune Selection Shapes Epstein–Barr Virus Population Structure
por: Wegner, Fanny, et al.
Publicado: (2019) -
RNA-seq Analysis of Host and Viral Gene Expression Highlights Interaction between Varicella Zoster Virus and Keratinocyte Differentiation
por: Jones, Meleri, et al.
Publicado: (2014) -
Decoding the Architecture of the Varicella-Zoster Virus Transcriptome
por: Braspenning, Shirley E., et al.
Publicado: (2020)