Cargando…

ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca(2+) release

Multiple functions of the endoplasmic reticulum (ER) essentially depend on ATP within this organelle. However, little is known about ER ATP dynamics and the regulation of ER ATP import. Here we describe real-time recordings of ER ATP fluxes in single cells using an ER-targeted, genetically encoded A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vishnu, Neelanjan, Jadoon Khan, Muhammad, Karsten, Felix, Groschner, Lukas N., Waldeck-Weiermair, Markus, Rost, Rene, Hallström, Seth, Imamura, Hiromi, Graier, Wolfgang F., Malli, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907277/ https://www.ncbi.nlm.nih.gov/pubmed/24307679 http://dx.doi.org/10.1091/mbc.E13-07-0433

Ejemplares similares

Intracellular Ca(2+) release decelerates mitochondrial cristae dynamics within the junctions to the endoplasmic reticulum
por: Gottschalk, Benjamin, et al.
Publicado: (2018)

Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca(2+) Uptake Pathways
por: Waldeck-Weiermair, Markus, et al.
Publicado: (2011)

Spatiotemporal Correlations between Cytosolic and Mitochondrial Ca(2+) Signals Using a Novel Red-Shifted Mitochondrial Targeted Cameleon
por: Waldeck-Weiermair, Markus, et al.
Publicado: (2012)

Molecularly Distinct Routes of Mitochondrial Ca(2+) Uptake Are Activated Depending on the Activity of the Sarco/Endoplasmic Reticulum Ca(2+) ATPase (SERCA)
por: Waldeck-Weiermair, Markus, et al.
Publicado: (2013)

The enigmatic ATP supply of the endoplasmic reticulum
por: Depaoli, Maria R., et al.
Publicado: (2018)

Generation of Red-Shifted Cameleons for Imaging Ca(2+) Dynamics of the Endoplasmic Reticulum
por: Waldeck-Weiermair, Markus, et al.
Publicado: (2015)

Endothelial mitochondria—less respiration, more integration
por: Groschner, Lukas N., et al.
Publicado: (2012)

Inhibition of Autophagy Rescues Palmitic Acid-induced Necroptosis of Endothelial Cells
por: Khan, Muhammad Jadoon, et al.
Publicado: (2012)

IP(3)-mediated STIM1 oligomerization requires intact mitochondrial Ca(2+) uptake
por: Deak, Andras T., et al.
Publicado: (2014)

Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca(2+) Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria
por: Madreiter-Sokolowski, Corina T., et al.
Publicado: (2016)

Mitochondrial Ca(2+) Uptake 1 (MICU1) and Mitochondrial Ca(2+) Uniporter (MCU) Contribute to Metabolism-Secretion Coupling in Clonal Pancreatic β-Cells
por: Alam, Muhammad Rizwan, et al.
Publicado: (2012)

Uncoupling protein 3 adjusts mitochondrial Ca(2+) uptake to high and low Ca(2+) signals
por: Waldeck-Weiermair, Markus, et al.
Publicado: (2010)

Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca(2+) Leak Directed to Mitochondria in Pancreatic Islets and β-Cells
por: Klec, Christiane, et al.
Publicado: (2019)

Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells
por: Depaoli, Maria R., et al.
Publicado: (2018)

UCP2 modulates single-channel properties of a MCU-dependent Ca(2+) inward current in mitochondria
por: Bondarenko, Alexander I., et al.
Publicado: (2015)

Mitochondrial–Endoplasmic Reticulum Interplay: A Lifelong On–Off Relationship?
por: Madreiter-Sokolowski, Corina T., et al.
Publicado: (2019)

Real-time visualization of distinct nitric oxide generation of nitric oxide synthase isoforms in single cells
por: Eroglu, Emrah, et al.
Publicado: (2017)

Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2+)
por: Waldeck-Weiermair, Markus, et al.
Publicado: (2015)

UCP2 and PRMT1 are key prognostic markers for lung carcinoma patients
por: Madreiter-Sokolowski, Corina T., et al.
Publicado: (2017)

GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells
por: Bondarenko, Alexander, et al.
Publicado: (2010)

Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction
por: Madreiter-Sokolowski, Corina T., et al.
Publicado: (2018)

Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics
por: Eroglu, Emrah, et al.
Publicado: (2016)

Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics
por: Oliva, Megan K., et al.
Publicado: (2020)

TRPV1 mediates cellular uptake of anandamide and thus promotes endothelial cell proliferation and network-formation
por: Hofmann, Nicole A., et al.
Publicado: (2014)

Studying mitochondrial Ca(2+) uptake – A revisit
por: Jean-Quartier, Claire, et al.
Publicado: (2012)

Mitochondrial Ca(2+) uniporter (MCU)-dependent and MCU-independent Ca(2+) channels coexist in the inner mitochondrial membrane
por: Bondarenko, Alexander I., et al.
Publicado: (2013)

Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes
por: Bischof, Helmut, et al.
Publicado: (2019)

Surveying the floodgates: estimating protein flux into the endoplasmic reticulum lumen in Saccharomyces cerevisiae
por: Vincent, Michael, et al.
Publicado: (2014)

AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum
por: Klein, Marie-Christine, et al.
Publicado: (2018)

MICU1 controls cristae junction and spatially anchors mitochondrial Ca(2+) uniporter complex
por: Gottschalk, Benjamin, et al.
Publicado: (2019)

Na(+)/Ca(2+) exchangers and Orai channels jointly refill endoplasmic reticulum (ER) Ca(2+) via ER nanojunctions in vascular endothelial cells
por: Di Giuro, Cristiana M. L., et al.
Publicado: (2017)

Genetic biosensors for imaging nitric oxide in single cells
por: Eroglu, Emrah, et al.
Publicado: (2018)

Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin
por: Opelt, Marissa, et al.
Publicado: (2016)

Visualization of Sirtuin 4 Distribution between Mitochondria and the Nucleus, Based on Bimolecular Fluorescence Self-Complementation
por: Ramadani-Muja, Jeta, et al.
Publicado: (2019)

High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast
por: Takaine, Masak, et al.
Publicado: (2022)

Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells
por: Eroglu, Emrah, et al.
Publicado: (2017)

Ca(2+) mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione
por: Lizák, Beáta, et al.
Publicado: (2020)

Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo
por: Bischof, Helmut, et al.
Publicado: (2017)

Endoplasmic reticulum-to-Golgi transitions upon herpes virus infection
por: Wild, Peter, et al.
Publicado: (2018)

PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca(2+) uptake in immortalized cells
por: Madreiter-Sokolowski, Corina T., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_i8q9vt9cukfbsdod9c6l0mju1d