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Automated Discovery of Tissue-Targeting Enhancers and Transcription Factors from Binding Motif and Gene Function Data
Identifying enhancers regulating gene expression remains an important and challenging task. While recent sequencing-based methods provide epigenomic characteristics that correlate well with enhancer activity, it remains onerous to comprehensively identify all enhancers across development. Here we in...
Autores principales: | Tuteja, Geetu, Moreira, Karen Betancourt, Chung, Tisha, Chen, Jenny, Wenger, Aaron M., Bejerano, Gill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907286/ https://www.ncbi.nlm.nih.gov/pubmed/24499934 http://dx.doi.org/10.1371/journal.pcbi.1003449 |
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