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Estimating the Probability of Polyreactive Antibodies 4E10 and 2F5 Disabling a gp41 Trimer after T Cell-HIV Adhesion

A few broadly neutralizing antibodies, isolated from HIV-1 infected individuals, recognize epitopes in the membrane proximal external region (MPER) of gp41 that are transiently exposed during viral entry. The best characterized, 4E10 and 2F5, are polyreactive, binding to the viral membrane and their...

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Detalles Bibliográficos
Autores principales:	Hu, Bin, Liao, Hua-Xin, Alam, S. Munir, Goldstein, Byron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907291/ https://www.ncbi.nlm.nih.gov/pubmed/24499928 http://dx.doi.org/10.1371/journal.pcbi.1003431

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