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Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin

BACKGROUND: Many biologically active compounds bind to plasma transport proteins, and this binding can be either advantageous or disadvantageous from a drug design perspective. Human serum albumin (HSA) is one of the most important transport proteins in the cardiovascular system due to its great bin...

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Detalles Bibliográficos
Autores principales: Sivertsen, Annfrid, Isaksson, Johan, Leiros, Hanna-Kirsti S, Svenson, Johan, Svendsen, John-Sigurd, Brandsdal, Bjørn Olav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907362/
https://www.ncbi.nlm.nih.gov/pubmed/24456893
http://dx.doi.org/10.1186/1472-6807-14-4