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MiR-21 Is under Control of STAT5 but Is Dispensable for Mammary Development and Lactation

Development of mammary alveolar epithelium during pregnancy is controlled by prolactin, through the transcription factors STAT5A/B that activate specific sets of target genes. Here we asked whether some of STAT5's functions are mediated by microRNAs. The miR-21 promoter sequence contains a bona...

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Detalles Bibliográficos
Autores principales: Feuermann, Yonatan, Kang, Keunsoo, Shamay, Avi, Robinson, Gertraud W., Hennighausen, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907398/
https://www.ncbi.nlm.nih.gov/pubmed/24497923
http://dx.doi.org/10.1371/journal.pone.0085123