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Leishmania-Mediated Inhibition of Iron Export Promotes Parasite Replication in Macrophages

Leishmania parasites infect macrophages, cells that play an important role in organismal iron homeostasis. By expressing ferroportin, a membrane protein specialized in iron export, macrophages release iron stored intracellularly into the circulation. Iron is essential for the intracellular replicati...

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Detalles Bibliográficos
Autores principales:	Ben-Othman, Rym, Flannery, Andrew R., Miguel, Danilo C., Ward, Diane M., Kaplan, Jerry, Andrews, Norma W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907422/ https://www.ncbi.nlm.nih.gov/pubmed/24497831 http://dx.doi.org/10.1371/journal.ppat.1003901

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