Cargando…
Mitogen-Induced B-Cell Proliferation Activates Chk2-Dependent G1/S Cell Cycle Arrest
B-cell activation and proliferation can be induced by a variety of extracellular stimuli. The fate of an activated B cell following mitogen stimulation can be dictated by the strength or duration of the signal, the expression of downstream signaling components necessary to promote proliferation, and...
Autores principales: | Nikitin, Pavel A., Price, Alexander M., McFadden, Karyn, Yan, Christopher M., Luftig, Micah A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907503/ https://www.ncbi.nlm.nih.gov/pubmed/24498068 http://dx.doi.org/10.1371/journal.pone.0087299 |
Ejemplares similares
-
Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest
por: van Jaarsveld, Marijn T. M., et al.
Publicado: (2020) -
An ATM/Chk2-mediated DNA damage responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells
por: Nikitin, Pavel, et al.
Publicado: (2010) -
DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1
por: Selvarajah, Jogitha, et al.
Publicado: (2014) -
An ATM/Chk2-mediated DNA damage responsive signaling pathway
suppresses Epstein-Barr virus transformation of primary human B
cells
por: Nikitin, Pavel A., et al.
Publicado: (2010) -
Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells
por: Sahu, R P, et al.
Publicado: (2009)