Increased Axonal Ribosome Numbers Is an Early Event in the Pathogenesis of Amyotrophic Lateral Sclerosis

Myelinating glia cells support axon survival and functions through mechanisms independent of myelination, and their dysfunction leads to axonal degeneration in several diseases. In amyotrophic lateral sclerosis (ALS), spinal motor neurons undergo retrograde degeneration, and slowing of axonal transp...

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Detalles Bibliográficos
Autores principales: Verheijen, Mark H. G., Peviani, Marco, Hendricusdottir, Rita, Bell, Erin M., Lammens, Martin, Smit, August B., Bendotti, Caterina, van Minnen, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907527/
https://www.ncbi.nlm.nih.gov/pubmed/24498056
http://dx.doi.org/10.1371/journal.pone.0087255

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