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Activation of the PI3K/mTOR Pathway Is Involved in Cystic Proliferation of Cholangiocytes of the PCK Rat

The polycystic kidney (PCK) rat is an animal model of Caroli’s disease as well as autosomal recessive polycystic kidney disease (ARPKD). The signaling pathways involving the mammalian target of rapamycin (mTOR) are aberrantly activated in ARPKD. This study investigated the effects of inhibitors for...

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Detalles Bibliográficos
Autores principales:	Ren, Xiang Shan, Sato, Yasunori, Harada, Kenichi, Sasaki, Motoko, Furubo, Shinichi, Song, Jing Yu, Nakanuma, Yasuni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907540/ https://www.ncbi.nlm.nih.gov/pubmed/24498161 http://dx.doi.org/10.1371/journal.pone.0087660

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