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KDT501, a Derivative from Hops, Normalizes Glucose Metabolism and Body Weight in Rodent Models of Diabetes

AIMS/HYPOTHESIS: We developed KDT501, a novel substituted 1,3-cyclopentadione chemically derived from hop extracts, and evaluated it in various in vitro and in vivo models of diabetes and insulin sensitivity. METHODS: KDT501 was evaluated for anti-inflammatory effects in monocyte/macrophage cells; a...

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Detalles Bibliográficos
Autores principales: Konda, Veera R., Desai, Anuradha, Darland, Gary, Grayson, Neile, Bland, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907559/
https://www.ncbi.nlm.nih.gov/pubmed/24498211
http://dx.doi.org/10.1371/journal.pone.0087848

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