Preeclampsia Is Associated with Alterations in the p53-Pathway in Villous Trophoblast

BACKGROUND: Preeclampsia (PE) is characterized by exaggerated apoptosis of the villous trophoblast of placental villi. Since p53 is a critical regulator of apoptosis we hypothesized that excessive apoptosis in PE is mediated by abnormal expression of proteins participating in the p53 pathway and tha...

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Detalles Bibliográficos
Autores principales: Sharp, Andrew N., Heazell, Alexander E. P., Baczyk, Dora, Dunk, Caroline E., Lacey, Helen A., Jones, Carolyn J. P., Perkins, Jonathan E., Kingdom, John C. P., Baker, Philip N., Crocker, Ian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907567/
https://www.ncbi.nlm.nih.gov/pubmed/24498154
http://dx.doi.org/10.1371/journal.pone.0087621

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