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Inhibition of Nucleotide Biosynthesis Potentiates the Antifungal Activity of Amphotericin B

The polyene antifungal agent Amphotericin B exhibits potent and broad spectrum fungicidal activity. However, high nephrotoxicity can hinder its administration in resource poor settings. Quantification of early fungicidal activity in studies of HIV patients with cryptococcosis demonstrate that 5-Fluo...

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Detalles Bibliográficos
Autores principales:	Banerjee, Dithi, Burkard, Lauren, Panepinto, John C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907572/ https://www.ncbi.nlm.nih.gov/pubmed/24498052 http://dx.doi.org/10.1371/journal.pone.0087246

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