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Osteogenic lineage restriction by osteoprogenitors cultured on nanometric grooved surfaces: The role of focal adhesion maturation()

The differentiation of progenitor cells is dependent on more than biochemical signalling. Topographical cues in natural bone extracellular matrix guide cellular differentiation through the formation of focal adhesions, contact guidance, cytoskeletal rearrangement and ultimately gene expression. Oste...

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Detalles Bibliográficos
Autores principales: Cassidy, John W., Roberts, Jemma N., Smith, Carol-Anne, Robertson, Mary, White, Kate, Biggs, Manus J., Oreffo, Richard O.C., Dalby, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907683/
https://www.ncbi.nlm.nih.gov/pubmed/24252447
http://dx.doi.org/10.1016/j.actbio.2013.11.008