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The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats

The hypocretin receptor (HcrtR) antagonist almorexant (ALM) has potent hypnotic actions but little is known about neurocognitive performance in the presence of ALM. HcrtR antagonists are hypothesized to induce sleep by disfacilitation of wake-promoting systems whereas GABA(A) receptor modulators suc...

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Detalles Bibliográficos
Autores principales:	Morairty, Stephen R., Wilk, Alan J., Lincoln, Webster U., Neylan, Thomas C., Kilduff, Thomas S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907703/ https://www.ncbi.nlm.nih.gov/pubmed/24550767 http://dx.doi.org/10.3389/fnins.2014.00003

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