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Interaction of Classical Platinum Agents with the Monomeric and Dimeric Atox1 Proteins: A Molecular Dynamics Simulation Study

We carried out molecular dynamics simulations and free energy calculations for a series of binary and ternary models of the cisplatin, transplatin and oxaliplatin agents binding to a monomeric Atox1 protein and a dimeric Atox1 protein to investigate their interaction mechanisms. All three platinum a...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaolei, Li, Chaoqun, Wang, Yan, Chen, Guangju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907799/ https://www.ncbi.nlm.nih.gov/pubmed/24362578 http://dx.doi.org/10.3390/ijms15010075

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