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Enhanced Antitumor Effects of Adenoviral-Mediated siRNA against GRP78 Gene on Adenosine-Induced Apoptosis in Human Hepatoma HepG2 Cells

Our previous studies show that adenosine-induced apoptosis is involved in endoplasmic reticulum stress in HepG2 cells. In this study, we have investigated whether knockdown of GRP78 by short hairpin RNA (shRNA) increases the cytotoxic effects of adenosine in HepG2 cells. The adenovirus vector-delive...

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Detalles Bibliográficos
Autores principales:	Wu, Ling-Fei, Guo, Yi-Tian, Zhang, Qing-Hua, Xiang, Meng-Qi, Deng, Wei, Ye, Yan-Qing, Pu, Ze-Jin, Feng, Jia-Lin, Huang, Guan-You
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907823/ https://www.ncbi.nlm.nih.gov/pubmed/24394318 http://dx.doi.org/10.3390/ijms15010525

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