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Dopamine D(4) Receptor Counteracts Morphine-Induced Changes in μ Opioid Receptor Signaling in the Striosomes of the Rat Caudate Putamen

The mu opioid receptor (MOR) is critical in mediating morphine analgesia. However, prolonged exposure to morphine induces adaptive changes in this receptor leading to the development of tolerance and addiction. In the present work we have studied whether the continuous administration of morphine ind...

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Detalles Bibliográficos
Autores principales: Suárez-Boomgaard, Diana, Gago, Belén, Valderrama-Carvajal, Alejandra, Roales-Buján, Ruth, Van Craenenbroeck, Kathleen, Duchou, Jolien, Borroto-Escuela, Dasiel O., Medina-Luque, José, de la Calle, Adelaida, Fuxe, Kjell, Rivera, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907881/
https://www.ncbi.nlm.nih.gov/pubmed/24451133
http://dx.doi.org/10.3390/ijms15011481