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Dopamine D(4) Receptor Counteracts Morphine-Induced Changes in μ Opioid Receptor Signaling in the Striosomes of the Rat Caudate Putamen
The mu opioid receptor (MOR) is critical in mediating morphine analgesia. However, prolonged exposure to morphine induces adaptive changes in this receptor leading to the development of tolerance and addiction. In the present work we have studied whether the continuous administration of morphine ind...
Autores principales: | Suárez-Boomgaard, Diana, Gago, Belén, Valderrama-Carvajal, Alejandra, Roales-Buján, Ruth, Van Craenenbroeck, Kathleen, Duchou, Jolien, Borroto-Escuela, Dasiel O., Medina-Luque, José, de la Calle, Adelaida, Fuxe, Kjell, Rivera, Alicia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907881/ https://www.ncbi.nlm.nih.gov/pubmed/24451133 http://dx.doi.org/10.3390/ijms15011481 |
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