Direct myocardial implantation of human embryonic stem cells in a dog model of Duchenne cardiomyopathy reveals poor cell survival in dystrophic tissue

Duchenne muscular dystrophy is characterized by progressive muscle weakness and early death resulting from dystrophin deficiency. Spontaneous canine muscular disorders are interesting settings to evaluate the relevance of innovative therapies in human using pre-clinical trials.

Detalles Bibliográficos
Autores principales: Habeler, W, Ghaleh, B, Barthelemy, I, Plancheron, A, Bizé, A, Carlos-Sampedrano, C, Chetboul, V, Berdeaux, A, Pucéat, M, Peschanski, M, Blot, S, Monville, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Stem cells and Regenerative Medicine 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908277/
https://www.ncbi.nlm.nih.gov/pubmed/24693175
Descripción
Sumario:Duchenne muscular dystrophy is characterized by progressive muscle weakness and early death resulting from dystrophin deficiency. Spontaneous canine muscular disorders are interesting settings to evaluate the relevance of innovative therapies in human using pre-clinical trials.

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