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Van der Woude syndrome- a syndromic form of orofacial clefting
Van der Woude Syndrome is the most common form of syndromic orofacial clefting, accounting for 2% of all cases, and has the phenotype that most closely resembles the more common non-syndromic forms. The syndrome has an autosomal dominant hereditary pattern with variable expressivity and a high degre...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908796/ https://www.ncbi.nlm.nih.gov/pubmed/24558537 http://dx.doi.org/10.4317/jced.50559 |
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author | Sudhakara Reddy, R. Ramesh, T. Vijayalaxmi, N. Lavanya Reddy, R. Swapna, L A. Rajesh Singh, T. |
author_facet | Sudhakara Reddy, R. Ramesh, T. Vijayalaxmi, N. Lavanya Reddy, R. Swapna, L A. Rajesh Singh, T. |
author_sort | Sudhakara Reddy, R. |
collection | PubMed |
description | Van der Woude Syndrome is the most common form of syndromic orofacial clefting, accounting for 2% of all cases, and has the phenotype that most closely resembles the more common non-syndromic forms. The syndrome has an autosomal dominant hereditary pattern with variable expressivity and a high degree of penetrance with cardinal clinical features of lip pits with a cleft lip, cleft palate, or both. This case report describes van der Woude syndrome in a 19 year old male patient with a specific reference to the various aspects of this condition, as clinical appearance, etiological factors (genetic aspects), differential diagnosis, investigative procedures and management. Key words:Cleft palate, cleft lip, lip pits, van der Woude syndrome, syndromic clefting. |
format | Online Article Text |
id | pubmed-3908796 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-39087962014-02-20 Van der Woude syndrome- a syndromic form of orofacial clefting Sudhakara Reddy, R. Ramesh, T. Vijayalaxmi, N. Lavanya Reddy, R. Swapna, L A. Rajesh Singh, T. J Clin Exp Dent Case Report Van der Woude Syndrome is the most common form of syndromic orofacial clefting, accounting for 2% of all cases, and has the phenotype that most closely resembles the more common non-syndromic forms. The syndrome has an autosomal dominant hereditary pattern with variable expressivity and a high degree of penetrance with cardinal clinical features of lip pits with a cleft lip, cleft palate, or both. This case report describes van der Woude syndrome in a 19 year old male patient with a specific reference to the various aspects of this condition, as clinical appearance, etiological factors (genetic aspects), differential diagnosis, investigative procedures and management. Key words:Cleft palate, cleft lip, lip pits, van der Woude syndrome, syndromic clefting. Medicina Oral S.L. 2012-04-01 /pmc/articles/PMC3908796/ /pubmed/24558537 http://dx.doi.org/10.4317/jced.50559 Text en Copyright: © 2012 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Sudhakara Reddy, R. Ramesh, T. Vijayalaxmi, N. Lavanya Reddy, R. Swapna, L A. Rajesh Singh, T. Van der Woude syndrome- a syndromic form of orofacial clefting |
title | Van der Woude syndrome- a syndromic form of orofacial clefting |
title_full | Van der Woude syndrome- a syndromic form of orofacial clefting |
title_fullStr | Van der Woude syndrome- a syndromic form of orofacial clefting |
title_full_unstemmed | Van der Woude syndrome- a syndromic form of orofacial clefting |
title_short | Van der Woude syndrome- a syndromic form of orofacial clefting |
title_sort | van der woude syndrome- a syndromic form of orofacial clefting |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908796/ https://www.ncbi.nlm.nih.gov/pubmed/24558537 http://dx.doi.org/10.4317/jced.50559 |
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