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A Simple Incidence-Based Method to Avoid Misinterpretation of Bovine Tuberculosis Incidence Trends in Great Britain

The incidence of bovine tuberculosis (TB) in Great Britain has generally been increasing in recent decades. Routine ante-mortem testing of cattle herds is required for disease surveillance and control, due to the asymptomatic nature of the infection. The Department for Environment, Food and Rural Af...

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Detalles Bibliográficos
Autores principales: Blake, Isobel M., Donnelly, Christl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908823/
https://www.ncbi.nlm.nih.gov/pubmed/24498536
http://dx.doi.org/10.1371/currents.outbreaks.6fd216fc24317f2ce04a7c5705a30c69
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author Blake, Isobel M.
Donnelly, Christl A.
author_facet Blake, Isobel M.
Donnelly, Christl A.
author_sort Blake, Isobel M.
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description The incidence of bovine tuberculosis (TB) in Great Britain has generally been increasing in recent decades. Routine ante-mortem testing of cattle herds is required for disease surveillance and control, due to the asymptomatic nature of the infection. The Department for Environment, Food and Rural Affairs (Defra) publishes TB incidence trends as the percentage of officially TB-free (OTF) herds tested per month with OTF status withdrawn due to post-mortem evidence of infection. This method can result in artefactual fluctuations. We have previously demonstrated an alternative method, that distributes incidents equally over the period of risk, provides a more accurate representation of underlying risk. However, this method is complex and it may not be sufficiently straightforward for use in the national statistics. Here we present a simple incidence-based method that adjusts for the time between tests and show it can provide a reasonable representation of the underlying risk without artefactual fluctuations.
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spelling pubmed-39088232014-02-03 A Simple Incidence-Based Method to Avoid Misinterpretation of Bovine Tuberculosis Incidence Trends in Great Britain Blake, Isobel M. Donnelly, Christl A. PLoS Curr Research The incidence of bovine tuberculosis (TB) in Great Britain has generally been increasing in recent decades. Routine ante-mortem testing of cattle herds is required for disease surveillance and control, due to the asymptomatic nature of the infection. The Department for Environment, Food and Rural Affairs (Defra) publishes TB incidence trends as the percentage of officially TB-free (OTF) herds tested per month with OTF status withdrawn due to post-mortem evidence of infection. This method can result in artefactual fluctuations. We have previously demonstrated an alternative method, that distributes incidents equally over the period of risk, provides a more accurate representation of underlying risk. However, this method is complex and it may not be sufficiently straightforward for use in the national statistics. Here we present a simple incidence-based method that adjusts for the time between tests and show it can provide a reasonable representation of the underlying risk without artefactual fluctuations. Public Library of Science 2014-01-24 /pmc/articles/PMC3908823/ /pubmed/24498536 http://dx.doi.org/10.1371/currents.outbreaks.6fd216fc24317f2ce04a7c5705a30c69 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research
Blake, Isobel M.
Donnelly, Christl A.
A Simple Incidence-Based Method to Avoid Misinterpretation of Bovine Tuberculosis Incidence Trends in Great Britain
title A Simple Incidence-Based Method to Avoid Misinterpretation of Bovine Tuberculosis Incidence Trends in Great Britain
title_full A Simple Incidence-Based Method to Avoid Misinterpretation of Bovine Tuberculosis Incidence Trends in Great Britain
title_fullStr A Simple Incidence-Based Method to Avoid Misinterpretation of Bovine Tuberculosis Incidence Trends in Great Britain
title_full_unstemmed A Simple Incidence-Based Method to Avoid Misinterpretation of Bovine Tuberculosis Incidence Trends in Great Britain
title_short A Simple Incidence-Based Method to Avoid Misinterpretation of Bovine Tuberculosis Incidence Trends in Great Britain
title_sort simple incidence-based method to avoid misinterpretation of bovine tuberculosis incidence trends in great britain
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908823/
https://www.ncbi.nlm.nih.gov/pubmed/24498536
http://dx.doi.org/10.1371/currents.outbreaks.6fd216fc24317f2ce04a7c5705a30c69
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