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Comparative Evaluation of Direct Thrombin and Factor Xa Inhibitors with Antiplatelet Agents under Flow and Static Conditions: An In Vitro Flow Chamber Model

Dabigatran and rivaroxaban are novel oral anticoagulants that specifically inhibit thrombin and factor Xa, respectively. The aim of this study is to elucidate antithrombotic properties of these anticoagulant agents under arterial and venous shear conditions. Whole blood samples treated with dabigatr...

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Detalles Bibliográficos
Autores principales:	Hosokawa, Kazuya, Ohnishi, Tomoko, Sameshima, Hisayo, Miura, Naoki, Koide, Takehiko, Maruyama, Ikuro, Tanaka, Kenichi A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908954/ https://www.ncbi.nlm.nih.gov/pubmed/24497951 http://dx.doi.org/10.1371/journal.pone.0086491

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