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Inhalation of the BK(Ca)-Opener NS1619 Attenuates Right Ventricular Pressure and Improves Oxygenation in the Rat Monocrotaline Model of Pulmonary Hypertension

BACKGROUND: Right heart failure is a fatal consequence of chronic pulmonary hypertension (PH). The development of PH is characterized by increased proliferation of vascular cells, in particular pulmonary artery smooth muscle cells (PASMCs) and pulmonary artery endothelial cells. In the course of PH,...

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Detalles Bibliográficos
Autores principales:	Revermann, Marc, Neofitidou, Skevi, Kirschning, Thomas, Schloss, Manuel, Brandes, Ralf P., Hofstetter, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909005/ https://www.ncbi.nlm.nih.gov/pubmed/24497961 http://dx.doi.org/10.1371/journal.pone.0086636

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