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Role of the single nucleotide polymorphism rs7903146 of TCF7L2 in inducing nonsense-mediated decay
BACKGROUND: The single nucleotide polymorphism (SNP) rs7903146 (C/T), located in intron 4 of the transcription factor 7-like 2 gene (TCF7L2), has been associated with an increased risk of developing Type 2 Diabetes, although the molecular mechanism remain elusive. The TCF7L2 gene is alternatively sp...
Autores principales: | Nicod, Nathalie, Pradas-Juni, Marta, Gomis, Ramon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909145/ https://www.ncbi.nlm.nih.gov/pubmed/24498581 http://dx.doi.org/10.1186/2193-1801-3-41 |
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