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C-Terminal Engineering of CXCL12 and CCL5 Chemokines: Functional Characterization by Electrophysiological Recordings

Chemokines are chemotactic cytokines comprised of 70–100 amino acids. The chemokines CXCL12 and CCL5 are the endogenous ligands of the CXCR4 and CCR5 G protein-coupled receptors that are also HIV co-receptors. Biochemical, structural and functional studies of receptors are ligand-consuming and the c...

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Detalles Bibliográficos
Autores principales:	Picciocchi, Antoine, Šiaučiūnaiteė-Gaubard, Lina, Petit-Hartlein, Isabelle, Sadir, Rabia, Revilloud, Jean, Caro, Lydia, Vivaudou, Michel, Fieschi, Franck, Moreau, Christophe, Vivès, Corinne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909184/ https://www.ncbi.nlm.nih.gov/pubmed/24498095 http://dx.doi.org/10.1371/journal.pone.0087394

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