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Negative Auto-Regulation of Myostatin Expression is Mediated by Smad3 and MicroRNA-27
Growth factors, such as myostatin (Mstn), play an important role in regulating post-natal myogenesis. In fact, loss of Mstn has been shown to result in increased post-natal muscle growth through enhanced satellite cell functionality; while elevated levels of Mstn result in dramatic skeletal muscle w...
Autores principales: | McFarlane, Craig, Vajjala, Anuradha, Arigela, Harikumar, Lokireddy, Sudarsanareddy, Ge, XiaoJia, Bonala, Sabeera, Manickam, Ravikumar, Kambadur, Ravi, Sharma, Mridula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909192/ https://www.ncbi.nlm.nih.gov/pubmed/24498167 http://dx.doi.org/10.1371/journal.pone.0087687 |
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