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Promoter DNA Methylation of Farnesoid X Receptor and Pregnane X Receptor Modulates the Intrahepatic Cholestasis of Pregnancy Phenotype

The intrahepatic cholestasis of pregnancy (ICP) is a multifactorial liver disorder which pathogenesis involves the interplay among abnormal bile acid (BA) levels, sex hormones, environmental factors, and genetic susceptibility. The dynamic nature of ICP that usually resolves soon after delivery sugg...

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Detalles Bibliográficos
Autores principales: Cabrerizo, Romina, Castaño, Gustavo O., Burgueño, Adriana L., Fernández Gianotti, Tomas, Gonzalez Lopez Ledesma, María Mora, Flichman, Diego, Pirola, Carlos J., Sookoian, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909199/
https://www.ncbi.nlm.nih.gov/pubmed/24498169
http://dx.doi.org/10.1371/journal.pone.0087697