Establishment and Validation of Whole-Cell Based Fluorescence Assays to Identify Anti-Mycobacterial Compounds Using the Acanthamoeba castellanii - Mycobacterium marinum Host-Pathogen System

Tuberculosis is considered to be one of the world’s deadliest disease with 2 million deaths each year. The need for new antitubercular drugs is further exacerbated by the emergence of drug-resistance strains. Despite multiple recent efforts, the majority of the hits discovered by traditional target-...

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Detalles Bibliográficos
Autores principales: Kicka, Sébastien, Trofimov, Valentin, Harrison, Christopher, Ouertatani-Sakouhi, Hajer, McKinney, John, Scapozza, Leonardo, Hilbi, Hubert, Cosson, Pierre, Soldati, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909256/
https://www.ncbi.nlm.nih.gov/pubmed/24498207
http://dx.doi.org/10.1371/journal.pone.0087834

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