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Phase I dose-escalation study of oral vinflunine in combination with erlotinib in pre-treated and unselected EGFR patients with locally advanced or metastatic non-small-cell lung cancer

BACKGROUND: Erlotinib, the epidermal growth factor receptor tyrosine kinase inhibitor, and the intra-venous vinflunine vinca alkaloid microtubule inhibitor have been shown to be effective in the setting of non-small-cell lung cancer (NSCLC) palliative patients with acceptable toxicities. This phase...

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Detalles Bibliográficos
Autores principales:	Krzakowski, M., Bennouna, J., Dansin, E., Kowalski, D., Hiret, S., Penel, N., Favrel, S., Tourani, J. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909260/ https://www.ncbi.nlm.nih.gov/pubmed/24220936 http://dx.doi.org/10.1007/s00280-013-2342-3

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