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Human but Not Mouse Hepatocytes Respond to Interferon-Lambda In Vivo

The type III interferon (IFN) receptor is preferentially expressed by epithelial cells. It is made of two subunits: IFNLR1, which is specific to IFN-lambda (IFN-λ) and IL10RB, which is shared by other cytokine receptors. Human hepatocytes express IFNLR1 and respond to IFN-λ. In contrast, the IFN-λ r...

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Detalles Bibliográficos
Autores principales:	Hermant, Pascale, Demarez, Céline, Mahlakõiv, Tanel, Staeheli, Peter, Meuleman, Philip, Michiels, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909289/ https://www.ncbi.nlm.nih.gov/pubmed/24498220 http://dx.doi.org/10.1371/journal.pone.0087906

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