MicroRNA-10a Is Down-Regulated by DNA Methylation and Functions as a Tumor Suppressor in Gastric Cancer Cells

BACKGROUND: MicroRNAs act as posttranscriptional regulators of gene expression in many biological processes. Their deregulations occur commonly in gastric cancer (GC). Although DNA methylation constitutes an important mechanism for microRNA deregulation in cancer, this field largely remains unexplor...

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Detalles Bibliográficos
Autores principales: Jia, Hongyan, Zhang, Zhengyi, Zou, Dongling, Wang, Bin, Yan, Yunmeng, Luo, Min, Dong, Lei, Yin, Haixin, Gong, Bei, Li, Zheng, Wang, Fang, Song, Wei, Liu, Changzheng, Ma, Yanni, Zhang, Junwu, Zhao, Haoliang, Li, Jianxiong, Yu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909310/
https://www.ncbi.nlm.nih.gov/pubmed/24498243
http://dx.doi.org/10.1371/journal.pone.0088057

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