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Differential Modulation of Arcuate Nucleus and Mesolimbic Gene Expression Levels by Central Leptin in Rats on Short-Term High-Fat High-Sugar Diet

OBJECTIVE: Leptin resistance is a common hallmark of obesity. Rats on a free-choice high-fat high-sugar (fcHFHS) diet are resistant to peripherally administered leptin. The aim of this study was to investigate feeding responses to central leptin as well as the associated changes in mRNA levels in hy...

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Detalles Bibliográficos
Autores principales:	van den Heuvel, José K., Eggels, Leslie, Fliers, Eric, Kalsbeek, Andries, Adan, Roger A. H., la Fleur, Susanne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909349/ https://www.ncbi.nlm.nih.gov/pubmed/24498181 http://dx.doi.org/10.1371/journal.pone.0087729

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