Microbial synthesized biodegradable PHBHHxPEG hybrid copolymer as an efficient intracellular delivery nanocarrier for kinase inhibitor

BACKGROUND: Protein Kinases are key regulators of cell function and play essential roles in the occurrence and development of many human diseases. Many kinase inhibitors have been used for molecular targeted treatment of those diseases such as cancer and inflammation. However, those highly hydrophob...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Xiao-Yun, Li, Ming-Chuan, Zhu, Xin-Liang, Fan, Fan, Wang, Lei-Lei, Ma, Jian-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909372/
https://www.ncbi.nlm.nih.gov/pubmed/24438107
http://dx.doi.org/10.1186/1472-6750-14-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909372/
https://www.ncbi.nlm.nih.gov/pubmed/24438107
http://dx.doi.org/10.1186/1472-6750-14-4

Ejemplares similares