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Effect of the local administration of betamethasone on pain, swelling and trismus after impacted lower third molar extraction. A randomized, triple blinded, controlled trial
Objectives: The aim of this study is to compare the analgesic and anti-inflammatory effects of the local postoperative administration of a single 12-mg dose of betamethasone after the surgical removal of impacted lower third molars. Study Design: A split-mouth, triple-blind, randomized, placebo-cont...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909432/ https://www.ncbi.nlm.nih.gov/pubmed/24121915 http://dx.doi.org/10.4317/medoral.19280 |
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author | Marques, José Pié-Sánchez, Jordi Figueiredo, Rui Valmaseda-Castellón, Eduard Gay-Escoda, Cosme |
author_facet | Marques, José Pié-Sánchez, Jordi Figueiredo, Rui Valmaseda-Castellón, Eduard Gay-Escoda, Cosme |
author_sort | Marques, José |
collection | PubMed |
description | Objectives: The aim of this study is to compare the analgesic and anti-inflammatory effects of the local postoperative administration of a single 12-mg dose of betamethasone after the surgical removal of impacted lower third molars. Study Design: A split-mouth, triple-blind, randomized, placebo-controlled clinical trial of 25 patients requiring the surgical removal of symmetrical lower third molars was performed. In the experimental side, a 12-mg dose of betamethasone was administered submucosally after the surgical procedure, while in the control side a placebo (sterile saline solution) was injected in the same area. To assess postoperative pain, visual analogue scales and the consumption of rescue analgesic were used. The facial swelling and trismus were evaluated by measuring facial reference distances and maximum mouth opening. Results: There were no significant differences between the two study groups regarding postoperative pain, facial swelling and trismus. Conclusions: The injection of a single dose of betamethasone does not seem to reduce pain, facial swelling and trismus after impacted lower third molar removal when compared to placebo. Key words:Third molar extraction, corticosteroids, betamethasone. |
format | Online Article Text |
id | pubmed-3909432 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-39094322014-02-10 Effect of the local administration of betamethasone on pain, swelling and trismus after impacted lower third molar extraction. A randomized, triple blinded, controlled trial Marques, José Pié-Sánchez, Jordi Figueiredo, Rui Valmaseda-Castellón, Eduard Gay-Escoda, Cosme Med Oral Patol Oral Cir Bucal Research Objectives: The aim of this study is to compare the analgesic and anti-inflammatory effects of the local postoperative administration of a single 12-mg dose of betamethasone after the surgical removal of impacted lower third molars. Study Design: A split-mouth, triple-blind, randomized, placebo-controlled clinical trial of 25 patients requiring the surgical removal of symmetrical lower third molars was performed. In the experimental side, a 12-mg dose of betamethasone was administered submucosally after the surgical procedure, while in the control side a placebo (sterile saline solution) was injected in the same area. To assess postoperative pain, visual analogue scales and the consumption of rescue analgesic were used. The facial swelling and trismus were evaluated by measuring facial reference distances and maximum mouth opening. Results: There were no significant differences between the two study groups regarding postoperative pain, facial swelling and trismus. Conclusions: The injection of a single dose of betamethasone does not seem to reduce pain, facial swelling and trismus after impacted lower third molar removal when compared to placebo. Key words:Third molar extraction, corticosteroids, betamethasone. Medicina Oral S.L. 2014-01 2013-10-13 /pmc/articles/PMC3909432/ /pubmed/24121915 http://dx.doi.org/10.4317/medoral.19280 Text en Copyright: © 2014 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Marques, José Pié-Sánchez, Jordi Figueiredo, Rui Valmaseda-Castellón, Eduard Gay-Escoda, Cosme Effect of the local administration of betamethasone on pain, swelling and trismus after impacted lower third molar extraction. A randomized, triple blinded, controlled trial |
title | Effect of the local administration of betamethasone
on pain, swelling and trismus after impacted lower third
molar extraction. A randomized, triple blinded, controlled trial |
title_full | Effect of the local administration of betamethasone
on pain, swelling and trismus after impacted lower third
molar extraction. A randomized, triple blinded, controlled trial |
title_fullStr | Effect of the local administration of betamethasone
on pain, swelling and trismus after impacted lower third
molar extraction. A randomized, triple blinded, controlled trial |
title_full_unstemmed | Effect of the local administration of betamethasone
on pain, swelling and trismus after impacted lower third
molar extraction. A randomized, triple blinded, controlled trial |
title_short | Effect of the local administration of betamethasone
on pain, swelling and trismus after impacted lower third
molar extraction. A randomized, triple blinded, controlled trial |
title_sort | effect of the local administration of betamethasone
on pain, swelling and trismus after impacted lower third
molar extraction. a randomized, triple blinded, controlled trial |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909432/ https://www.ncbi.nlm.nih.gov/pubmed/24121915 http://dx.doi.org/10.4317/medoral.19280 |
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