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Impact of aging in cancer immunotherapy: The importance of using accurate preclinical models
Cancer immunotherapy holds great promise, yet its efficacy and applicability can be hampered by the rise of systemic toxicities. We have recently shown that the lethal side effects of cancer immunotherapy are markedly exacerbated with aging. Blocking tumor necrosis factor α or macrophages can allevi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909540/ https://www.ncbi.nlm.nih.gov/pubmed/24498569 http://dx.doi.org/10.4161/onci.27186 |