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Doppler Surrogate Endoscopy for Screening Esophageal Varices in Patients With Cirrhosis
BACKGROUND: Portal hypertension is a common consequence of hepatic cirrhosis, which causes esophageal varices. Bleeding from varices has a high mortality rate. The present gold standard for diagnosing varices is endoscopy. Considering endoscopy side effects and patients' low acceptance, there h...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909634/ https://www.ncbi.nlm.nih.gov/pubmed/24497873 http://dx.doi.org/10.5812/hepatmon.11237 |
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author | Akhavan Rezayat, Kambiz Mansour Ghanaei, Fariborz Alizadeh, Ahmad Shafaghi, Afshin Babaei Jandaghi, Ali |
author_facet | Akhavan Rezayat, Kambiz Mansour Ghanaei, Fariborz Alizadeh, Ahmad Shafaghi, Afshin Babaei Jandaghi, Ali |
author_sort | Akhavan Rezayat, Kambiz |
collection | PubMed |
description | BACKGROUND: Portal hypertension is a common consequence of hepatic cirrhosis, which causes esophageal varices. Bleeding from varices has a high mortality rate. The present gold standard for diagnosing varices is endoscopy. Considering endoscopy side effects and patients' low acceptance, there have been always efforts for finding alternative diagnostic methods including Doppler ultrasonography (US). OBJECTIVES: The aim of the present study was to evaluate changes of Doppler indices in cirrhotic patients with and without esophageal varices. PATIENTS AND METHODS: Sixty six patients with known cirrhosis entered this cross-sectional study. Gastroscopy was performed for patients, and the first questionnaire was filled based on the Japanese Portal Hypertension Society guidelines. Then patients were referred for Doppler US of splenoportal system, and information was documented in the second questionnaire. RESULTS: Forty-four patients were male and 22 female. Forty six patients had esophageal varices, and 20 did not. There were no significant associations between splenoportal indices found by Doppler US, and presence of esophageal varices in patients. However, we found a negative association between platelet ratio to spleen diameter, and to splenic vein diameter. CONCLUSIONS: Neither of studied variables was perfect to differentiate cirrhotic patients with and without EVs. Endoscopy is still the gold standard diagnostic method for diagnosing esophageal varices in patients with cirrhosis. It seems that some of the splenoportal Doppler indices are promising, but more research and evaluation is necessary. |
format | Online Article Text |
id | pubmed-3909634 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Kowsar |
record_format | MEDLINE/PubMed |
spelling | pubmed-39096342014-02-04 Doppler Surrogate Endoscopy for Screening Esophageal Varices in Patients With Cirrhosis Akhavan Rezayat, Kambiz Mansour Ghanaei, Fariborz Alizadeh, Ahmad Shafaghi, Afshin Babaei Jandaghi, Ali Hepat Mon Research Article BACKGROUND: Portal hypertension is a common consequence of hepatic cirrhosis, which causes esophageal varices. Bleeding from varices has a high mortality rate. The present gold standard for diagnosing varices is endoscopy. Considering endoscopy side effects and patients' low acceptance, there have been always efforts for finding alternative diagnostic methods including Doppler ultrasonography (US). OBJECTIVES: The aim of the present study was to evaluate changes of Doppler indices in cirrhotic patients with and without esophageal varices. PATIENTS AND METHODS: Sixty six patients with known cirrhosis entered this cross-sectional study. Gastroscopy was performed for patients, and the first questionnaire was filled based on the Japanese Portal Hypertension Society guidelines. Then patients were referred for Doppler US of splenoportal system, and information was documented in the second questionnaire. RESULTS: Forty-four patients were male and 22 female. Forty six patients had esophageal varices, and 20 did not. There were no significant associations between splenoportal indices found by Doppler US, and presence of esophageal varices in patients. However, we found a negative association between platelet ratio to spleen diameter, and to splenic vein diameter. CONCLUSIONS: Neither of studied variables was perfect to differentiate cirrhotic patients with and without EVs. Endoscopy is still the gold standard diagnostic method for diagnosing esophageal varices in patients with cirrhosis. It seems that some of the splenoportal Doppler indices are promising, but more research and evaluation is necessary. Kowsar 2014-01-16 /pmc/articles/PMC3909634/ /pubmed/24497873 http://dx.doi.org/10.5812/hepatmon.11237 Text en Copyright © 2014, BRCGL. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Akhavan Rezayat, Kambiz Mansour Ghanaei, Fariborz Alizadeh, Ahmad Shafaghi, Afshin Babaei Jandaghi, Ali Doppler Surrogate Endoscopy for Screening Esophageal Varices in Patients With Cirrhosis |
title | Doppler Surrogate Endoscopy for Screening Esophageal Varices in Patients With Cirrhosis |
title_full | Doppler Surrogate Endoscopy for Screening Esophageal Varices in Patients With Cirrhosis |
title_fullStr | Doppler Surrogate Endoscopy for Screening Esophageal Varices in Patients With Cirrhosis |
title_full_unstemmed | Doppler Surrogate Endoscopy for Screening Esophageal Varices in Patients With Cirrhosis |
title_short | Doppler Surrogate Endoscopy for Screening Esophageal Varices in Patients With Cirrhosis |
title_sort | doppler surrogate endoscopy for screening esophageal varices in patients with cirrhosis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909634/ https://www.ncbi.nlm.nih.gov/pubmed/24497873 http://dx.doi.org/10.5812/hepatmon.11237 |
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