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Overexpression of recombinant HIV-1 Subtype C Tat and Nef in a Salmonella vaccine vector
Tat and Nef are very important regulatory proteins of HIV-1. They enhance viral replication and down-regulate expression of MHC Class I molecules, respectively. The antigens are now considered to be targets for HIV vaccine development. The expression of Tat and Nef in Salmonella vaccines has not pre...
Autores principales: | Chin’ombe, Nyasha, Lebeko, Maribanyana, Kgatle, Mankgopo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909692/ https://www.ncbi.nlm.nih.gov/pubmed/24498468 http://dx.doi.org/10.11604/pamj.2013.16.19.2759 |
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