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NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses()

Uncontrolled fibrosis in organs like heart, kidney, liver and lung is detrimental and may lead to end-stage organ failure. Currently there is no effective treatment for fibrotic disorders. Transforming growth factor (TGF)-β has a fundamental role in orchestrating the process of fibrogenesis; however...

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Detalles Bibliográficos
Autores principales: Jiang, Fan, Liu, Guei-Sheung, Dusting, Gregory J., Chan, Elsa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909817/
https://www.ncbi.nlm.nih.gov/pubmed/24494202
http://dx.doi.org/10.1016/j.redox.2014.01.012