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Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5()

Cytochrome P450 gene expression is altered by various chemical compounds. In this study, we used nuclear factor erythroid 2-related factor 2 (Nrf2)–deficient (Nrf2(−⧸−)) mice to investigate the involvement of Nrf2 in Cyp2b10 and Cyp2a5 gene expression. Phorone, an Nrf2 activator, strongly increased...

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Detalles Bibliográficos
Autores principales: Ashino, Takashi, Ohkubo-Morita, Haruyo, Yamamoto, Masayuki, Yoshida, Takemi, Numazawa, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909825/
https://www.ncbi.nlm.nih.gov/pubmed/24494203
http://dx.doi.org/10.1016/j.redox.2013.12.025